Anthropic opens life sciences verification program
Anthropic is opening its Life Sciences Verification Program to vetted biology teams, granting access to Mythos, Opus and Sonnet models with loosened bio-safeguards and, for approved projects, none at all.
Anthropic has opened applications for its Life Sciences Verification Program (LSVP), a beta scheme that grants vetted life science teams access to Mythos, Opus and Sonnet models running refined classifiers that are more permissive for biology work than the generally available Fable models. Dozens of organizations were already onboarded through an earlier access program; the beta is open to teams and institutions, with Pro and Max individual plans promised later.
Applicants are reviewed on research credentials, security standards and ethical research oversight, then apply for one of two grant types, usable across Claude Science, Claude.ai, Claude Code and the API. Standard Use covers most biology R&D, extends to a whole team, renews annually, and applies to Mythos 5.1, Opus 5 and Sonnet 5 plus future models. High-risk Use is a per-project add-on, renewed every six months, that removes all safeguards blocking life sciences requests; it is available today for Opus 5 and Sonnet 5, while Mythos high-risk access remains limited to a small set of additionally vetted entities pending work with the US government. Cyber classifiers and other safeguards stay in place.
The structural change is enforcement: inside LSVP, Anthropic shifts from real-time blocking to offline monitoring of usage against each grant's stated use cases, flagging out-of-scope activity to organization admins under pre-agreed remediation timeframes. The announcement text available here cuts off mid-sentence on the data retention that offline monitoring requires.